Opioids
The Crisis Continues
Despite widespread efforts over many years, opioid overuse remains dangerously high.
~154M
Opioid prescriptions dispensed by pharmacies in 20191
80%
Percentage of heroin users who first misused prescription opioids2
75%
Opioid overdose deaths as a percentage of all drug overdose deaths in 20203
29%
Increase in drug overdose deaths in 2020 compared to 20193

Stop Addiction Before it Starts
So far, most resources in the fight against opioid overuse have been dedicated to helping people who are already addicted. We believe prevention has been overlooked—and we’re out to change that.
Genetics:
The Missing Piece
Prescription opioids are effective for managing pain. But for some people, they bring an increased risk of addiction. Which people? Some of the answer is found in our DNA.

Uncovering
Hidden Risk
What if patients and healthcare providers could find out who is at increased genetic risk for opioid addiction before a prescription is written? Now they can.
Uncovering
Hidden Risk
What if patients and healthcare providers could find out who is at increased genetic risk for opioid addiction before a prescription is written? Now they can.
Designed for Decisions
AvertD™ is a clinically validated genetic test that identifies an individual’s risk for developing Opioid Use Disorder (OUD). When making prescribing decisions, AvertD offers an objective method of identifying which patients may be at increased risk of developing opioid addiction—so patients and their providers can tailor pain management plans accordingly.
1. IQVIA Xponent market research services. ©IQVIA 2020. All rights reserved.
2. Opioid Overdose Crisis. National Institute on Drug Abuse. Available online at: https://www.drugabuse.gov/drugs-abuse/opioids/opioid-overdose-crisis
3. Ahmad FB, Rossen LM, Sutton P. Provisional drug overdose death counts. National Center for Health Statistics. 2021. Accessed at https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm on July 26, 2021.
Read Our Latest Blog
Why You (and Your Doctor) Should #KnowYourRisk for Opioid Addiction
Opioids are often prescribed following surgery or injury to manage moderate to severe pain—but they come with a risk of addiction. While everyone who takes prescription opioids is at risk for addiction, that risk is higher for some people than others.
What is Pharmacogenomics (PGx) Testing?
Just as your genes determine the basic truths of your biology—things like your height and eye and hair color—genes also determine how your body reacts to certain medications. No medication works the same for everyone; in fact, results can vary widely.
What is an FDA Breakthrough Device Designation?
FDA Breakthrough Device designation is granted to novel medical devices that have the potential to provide more effective treatment or diagnosis of life-threatening or irreversibly debilitating diseases or conditions.